The Short Sleep ​Study​: A non-interventional study of fecal microbiota in Natural Short Sleepers​

This research study explores the unique gut bacteria of “Natural Short Sleepers”—rare individuals who sleep less than average yet wake up feeling refreshed without daytime fatigue. By studying their gut microbiome, we aim to uncover insights that could help improve health outcomes for people with inadequate sleep.

As a participant, you’ll maintain your normal sleep habits, with no treatments, no overnight visits to a sleep clinic, and no interventions required. Eligible participants will receive up to $300 and an Oura Ring (yours to keep, ~$300 value) in appreciation for their time and commitment

Study overview

Your Participation

This study consists of: Screening Period, enrollment visit, 2-5 day run-in period, 10-day study period

Compensation

If you complete all the study activities you will receive up to $300 and an Oura ring for your time

Timeline

Total timeline up to 38 days. Enroll by 31/Dec/2025

Study Location

Long Island - New York

Houston - Texas

Health Insights: Watch & Learn

Next Steps

Step 1: Pre-screening and Screening

Complete a 20-minute pre-screening survey to see if you might qualify. If eligible, you'll automatically enter a 14-day screening period where you'll track your sleep patterns through daily diaries and questionnaires.

Step 2: Enrollment visit

Setup, training, and first blood sample

Step 3: 2-5 day run-in period

Practice with device and sleep tracking at home

Step 4: 10-day study period

Sample collection and daily tracking

Step 5: Final Visit

Complete study and collect compensation

Patient Stories

Robert

Cardiovascular Research Trial

"The cardiovascular clinical trial I participated in provided me with access to the latest treatments before they became widely available. The through screening process and ongoing support gave me confidence in the study."

Maria

Autoimmune Treatment Study

"Joining this crinical trial for my autoimmune condition was life-changing. The research team's expertise and dedication were evident from day one. I received personalized care and monitoring that exceeded my expectations."

David

Migraine Prevention Trial

"The migraine study I participated in provided me with access to innovative treatments that significantly reduced my symptoms. The study coordinators were professional and made me feel comfortable throughout the process."

Robert

Cardiovascular Research Trial

"The cardiovascular clinical trial I participated in provided me with access to the latest treatments before they became widely available. The through screening process and ongoing support gave me confidence in the study."

Maria

Autoimmune Treatment Study

"Joining this crinical trial for my autoimmune condition was life-changing. The research team's expertise and dedication were evident from day one. I received personalized care and monitoring that exceeded my expectations."

David

Migraine Prevention Trial

"The migraine study I participated in provided me with access to innovative treatments that significantly reduced my symptoms. The study coordinators were professional and made me feel comfortable throughout the process."

Who is this study for?

You may be eligible if you meet the following requirements:
Age
20-50 years old if male and 20-45 if female
Sleep Schedule
Sleep <6 hours per night and wake up refreshed
Employed
Has a consistent daytime schedule
BMI between 18.5-35
Generally healthy with no chronic GI conditions
Regular bowel movements (at least 5 days a week) with no chronic symptoms
Maintain stable routine and no planned travel during study
Sleep disorders, medications, or supplements affecting sleep
Sleep disrupted by children, pets, or shift work
Antibiotics (past 3 months), probiotics (past 2 weeks), or PPIs (past 2 weeks)
Medications significantly affecting sleep or gut health
Additional eligibility criteria will be reviewed during the screening process

Do you think you’re eligible?

Complete a quick questionnaire to assess if you meet the study criteria and start benefitting from this innovative treatment.

Find a clinic near you

Clinics near you:

Start by entering a location or use your current position.

Your questions answered

Accordion

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What Makes Someone a Natural Short Sleeper?

You might be a Natural Short Sleeper if you:

What’s Required - At-Home Activities

You'll track your natural sleep patterns and provide samples from the comfort of your home:

What’s Required - On-Site Visit

Visit 1:

Visit 2:

Compensation

Up to $300 + Oura Ring (~$300 value)

Payment Schedule:

Ready to Participate?

Natural Short Sleepers are rare - if this describes you, your participation could provide valuable insights into sleep and health. Complete the pre-screening survey to see if you qualify for this unique research opportunity.

Questions? Contact our study team at shortsleep@lindushealth.com