The Short Sleep ​Study​: A non-interventional study of fecal microbiota in Natural Short Sleepers​

This research study explores the unique gut bacteria of “Natural Short Sleepers”—rare individuals who sleep less than average yet wake up feeling refreshed without daytime fatigue. By studying their gut microbiome, we aim to uncover insights that could help improve health outcomes for people with inadequate sleep.

As a participant, you’ll maintain your normal sleep habits, with no treatments, no overnight visits to a sleep clinic, and no interventions required. Eligible participants will receive up to $300 and an Oura Ring (yours to keep, ~$300 value) in appreciation for their time and commitment

Study overview

Your Participation

Participants will complete online questionnaires, daily eDiaries, sleep diary tracking, blood draws (2 times), and at-home fecal sample collections (7 times) over approximately 35 days of active participation.

Compensation

Participants receive up to $300 upon study completion, plus $50 for completing the 14-day screening period, regardless of eligibility to continue.

Timeline

The study includes a 14-day virtual screening period followed by approximately 10 days of active on-site participation, totaling around 35 days.

Study Location

The study involves both virtual/at-home components and in-person on-site visits for blood draws, with remote sleep and fecal sample monitoring conducted from home.

Health Insights: Watch & Learn

Next Steps

Step 1: Pre-screening and Screening

Complete a 10–15 minute online survey to assess eligibility, followed by an online questionnaire covering demographics, medical history, medications, and sleep habits.

Step 2: Pre-screening Passed!

If you pass the pre-screening survey, you will be asked to review an informed consent to enter the 14-day screening period of the study to further determine if you are eligible to continue.

Step 3: Consent and authorization

Review study information and provide your consent to join the study.

Patient Stories

Robert

Cardiovascular Research Trial

"The cardiovascular clinical trial I participated in provided me with access to the latest treatments before they became widely available. The through screening process and ongoing support gave me confidence in the study."

Maria

Autoimmune Treatment Study

"Joining this crinical trial for my autoimmune condition was life-changing. The research team's expertise and dedication were evident from day one. I received personalized care and monitoring that exceeded my expectations."

David

Migraine Prevention Trial

"The migraine study I participated in provided me with access to innovative treatments that significantly reduced my symptoms. The study coordinators were professional and made me feel comfortable throughout the process."

Robert

Cardiovascular Research Trial

"The cardiovascular clinical trial I participated in provided me with access to the latest treatments before they became widely available. The through screening process and ongoing support gave me confidence in the study."

Maria

Autoimmune Treatment Study

"Joining this crinical trial for my autoimmune condition was life-changing. The research team's expertise and dedication were evident from day one. I received personalized care and monitoring that exceeded my expectations."

David

Migraine Prevention Trial

"The migraine study I participated in provided me with access to innovative treatments that significantly reduced my symptoms. The study coordinators were professional and made me feel comfortable throughout the process."

Who is this study for?

You may be eligible if you meet the following requirements:
Sex
Male or pre-menopausal female
Age
Males 20-50; pre-menopausal females 20-45
Region
United States
Men between 20 and 50 years old
Pre-menopausal women between 20 and 45 years old
Generally healthy
Maintain a steady lifestyle and routine
Wake up feeling refreshed
Diagnosed with a sleep disorder
Diagnosed with a gastrointestinal disorder
Diagnosed with a neurodegenerative disease or disorder affecting sleep
Pregnant or breastfeeding or planning to become pregnant
Additional eligibility criteria will be reviewed during the screening process

Do you think you’re eligible?

Complete a quick questionnaire to assess if you meet the study criteria and start benefitting from this innovative treatment.

Find a clinic near you

Clinics near you:

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Your questions answered

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What is a clinical trial?

A clinical trial is a research study that helps develop and test new medical treatments, devices, or tests to determine if they are safe and effective.

Who is International Flavors & Fragrances Inc.

International Flavors & Fragrances Inc., (IFF). A major U.S. based speciality chemicals company, headquartered in New York, best known for creating flavors and fragrances used in food, beverages, personal care, and household products around the world. Beyond flavors and fragrances, the company operates in areas such as health and biosciences, food ingredients, and pharma solutions.

Who is Lindus Health?

Lindus Health is a contract research organization that manages clinical trials. The team coordinates study recruitment, site and virtual operations, and data collection, which may involve mobile phlebotomy, virtual enrollment, and medical record collection for home based participation.

What is Short Sleep  and why is this research important?

This Short Sleep Study aims to understand how sleep patterns affect gut bacteria (microbiota) and to explore potential opportunities to improve health outcomes for people with poor sleep. 

This research is important because modern lifestyles often conflict with natural sleep patterns, impacting productivity and mental health. By understanding how  those with short sleep function and identifying supportive interventions, the study helps inform product development in wellness, home, and personal care while contributing to broader conversations about sleep health and performance.

Can I withdraw from the study?

Yes, at any time without penalty or effect on your medical care. You can request your samples be destroyed at any time during the study.