Check Eligibility
Night Owl Sleep and Microbiome Study
This research study aims to understand how sleep patterns affect gut bacteria (microbiota) and to explore potential opportunities to improve health outcomes for people with inadequate sleep. The study will compare the microbiomes of people who typically get sufficient sleep (7-9 hours per night) with those of people who get less sleep (5-7 hours per night).
If you qualify to participate in the trial, you will receive up to $575 total for participating. You will also be given an Oura ring to use throughout the study and keep at the end of the trial. The study will involve some remote questionnaires followed by visits to a site over the course of about 6 weeks total. Some at-home digital surveys and activities will also be involved.
Study overview
Your Participation
Participants will complete online questionnaires, daily eDiaries, sleep diary tracking, blood draws (3 times), and at-home fecal sample collections (8 times) over approximately 47 days of active participation.
Compensation
Participants receive up to $575 upon study completion, including $50 for completing the 14-day screening period, regardless of eligibility to continue.
Timeline
The study includes a 14-day virtual screening period followed by approximately 28 days of active on-site participation, totaling around 47 days.
Study Location
The study involves both virtual/at-home components and in-person on-site visits for blood draws, with remote sleep and fecal sample monitoring conducted from home.
Health Insights: Watch & Learn
Patient Stories
Who is this study for?
You may be eligible if you meet the following requirements:
Sex
Male or pre-menopausal female
Age
Males 20–50; pre-menopausal females 20–45
Region
United States
Men between 20 and 50 years old
Pre-menopausal women between 20 and 45 years old
Generally healthy
Maintain a steady lifestyle and routine
Have generally uninterrupted sleep
Diagnosed with a sleep disorder
Diagnosed with a gastrointestinal disorder
Diagnosed with a neurodegenerative disease
Diagnosed with a neuropsychiatric disease or disorder affecting sleep
Pregnant or breastfeeding or planning to become pregnant
Additional eligibility criteria will be reviewed during the screening process
Your questions answered
Accordion
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What is a clinical trial?
A clinical trial is a research study that helps develop and test new medical treatments, devices, or tests to determine if they are safe and effective. This study is developing a screening test to predict preeclampsia risk early in pregnancy. Your participation provides the blood samples and health information needed to create and validate this test.
Who is IFF?
International Flavors & Fragrances Inc., (IFF). A major U.S. based speciality chemicals company, headquartered in New York, best known for creating flavors and fragrances used in food, beverages, personal care, and household products around the world. Beyond flavors and fragrances, the company operates in areas such as health and biosciences, food ingredients, and pharma solutions.
Who is Lindus Health?
Lindus Health is a contract research organization that manages clinical trials. The team coordinates study recruitment, site and virtual operations, and data collection, which may involve mobile phlebotomy, virtual enrollment, and medical record collection for home based participation.
What is the NightOwl Study and why is this research important?
This study examines individuals with evening chronotypes - commonly known as “night owls.” The study explores how staying up late affects mood cognitive performance, stress levels, and overall well-being.
This research is important because modern lifestyles often conflict with natural sleep patterns, impacting productivity and mental health. By understanding how night owls function and identifying supportive interventions, the study helps inform product development in wellness, home, and personal care while contributing to broader conversations about sleep health and performance.
Can I withdraw from the study?
Yes, at any time without penalty or effect on your medical care.